Site Activation Manager

Site Activation Manager

Location

Mexico City

Reference: JR161604

About the role

Hybrid - Mexico City

At ICON Strategic Solutions, you will work in a sponsor-dedicated model, supported by ICON’s global expertise.

As the world’s largest FSP organisation, with over 90 sponsor partnerships, we offer stability, career development and a collaborative environment where your work contributes to the development of treatments that benefit patients worldwide.

The Site Activation Manager is a sponsor-dedicated role delivered through a partnership with ICON and responsible for Northam study start-up and amendment activities. The role builds strong relationships with investigative sites, drives essential document collection and quality review, supports country and site ICF development and negotiation, ensures REB submission readiness and approval follow-up, manages amendment implementation, and partners cross-functionally to achieve timely site activation and amendment implementation.

What You Will Do:

Your focus will be on coordinating site start-up and activation delivery, resolving issues, and developing team capability.

Key responsibilities include:

• Build strong working relationships with investigative sites and support a positive sponsor-site experience throughout start-up.
• Collect, review, QC, and file essential documents required for submission and activation.
• Review and negotiate ICF changes with sites and stakeholders; manage translations, checklists, filing, and amendment updates as required.
• Ensure REB submissions are made and approval documentation is complete and activation-ready.
• Support regulatory and clinical trial start-up activities across the US and Canada, including coordination of submission, approval, and study activation workflows.
• Collaborate with sites and internal stakeholders to set and achieve Regulatory Greenlight (RGL) goals that support timely site activation.
• Escalate risks, manage timelines, and maintain accurate documentation and tracking in systems such as CTMS and the eTMF.

Your Profile:

You will have solid site start-up and activation experience, with the ability to manage competing priorities and develop your team.

Required qualifications and experience:

• Clinical trial start-up experience in a site-facing or dedicated site role.
• Solid understanding of ICH GCP, applicable ethics committee requirements (IRB/REB), and regulatory submission processes across the United States and Canada.
• Fluency in English.
• Experience with essential document collection, QC, and filing.
• Experience with ICF review, negotiation, and amendment management.
• Strong cross-functional collaboration and stakeholder management skills within a sponsor-partner operating model involving ICON.

What ICON can offer you: Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent.

In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.

Our benefits examples include:

• Various annual leave entitlements
• A range of health insurance offerings to suit you and your family’s needs.
• Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
• Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family’s well-being.
• Life assurance
• Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others.

Visit our careers site to read more about the benefits ICON offers.

At ICON, inclusion & belonging are fundamental to our culture and values. We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here

Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there’s every chance you’re exactly what we’re looking for here at ICON whether it is for this or other roles.