Senior Technical Program Manager, AI Security

About the Role Moderna is seeking a Senior Technical Program Manager (TPM) to drive project and program management of AI-readiness initiatives at Moderna globally. We’re looking for someone with a high level of integrity and personal accountability, strong interpersonal skills, and infrastructure technology domain expertise. What You'll Do

• Program Management – take a structured, data-driven, and risk-based approach to program scoping, execution, and reporting.
• Kick off and successfully manage multiple, simultaneous, complex, high-visibility workstreams with full ownership, effective collaboration, and good process.
• Build processes, templates, and structure, or leverage existing ones as appropriate.
• Manage vendors, schedule, scope, and cost.
• Measure program success (or lack thereof) and risks using data and facts.
• Provide balanced risk remediation strategies and recommendations and drive risk mitigation.
• Develop and maintain close stakeholder relationships and build influence to drive the appropriate outcomes across Moderna.
• Provide clear, accurate, consistent, and timely communications.
• Advance good infrastructure and security practices and culture.
• Partner Collaboration - work with Cybersecurity, Builder Tools & Platforms, Infrastructure, Identity & Endpoint Engineering, GRC, AI Engineering, Data, Enablement/L&D, software engineering, and business stakeholders to manage and drive improvement projects in a structured and predictable manner.
• Manage multiple initiatives to oversee the architecture and lifecycle of enterprise AI systems, including agent identity, tool authorization, and secure development practices; to drive governance frameworks that define permitted AI use, contextual standards, and regulatory alignment — including GxP where applicable; and to ensure end-to-end observability and monitoring of AI agents in production.
• Own the operating model for AI enablement programs, including pilots, cohorts, and phased rollouts, and partner with Enablement/L&D teams to shape role‑based learning paths for AI builders.
• Actively contribute to creating a more inclusive culture and environment at Moderna; endorse, create, and maintain antiracist policies and processes. What We're Looking For
• Experience: 8+ years in Technical Program Management, Engineering Program Management, or similar roles in AI/ML-heavy environments.
• Technical Depth: Strong understanding of AI/ML systems, including model training pipelines, LLMs, MLOps, data pipelines, and cloud infrastructure.
• Strong understanding of AI/ML development workflows, AI-assisted engineering tools, or modern software development platforms.
• Demonstrated technical depth, problem-solving capabilities, and stakeholder and vendor management skills.