About this role
About the Role In this vital role, you will join the Predictive Biology team as a hands-on scientist focused on building genetically engineered human induced pluripotent stem cell (iPSC) models to support target discovery, target validation, and mechanism-of-action studies. You will troubleshoot complex systems, improve current workflows, and help drive the next wave of innovation in human stem cell model engineering. What You'll Do
- Develop genetically defined iPSC model systems, including reporter, tagged, loss-of-function, disease-relevant, inducible, or otherwise perturbable models.
- Define and interpret fit-for-purpose validation strategies to determine whether engineered models are suitable for downstream biological studies.
- Identify, troubleshoot, and solve technical and biological failure modes, including poor editing outcomes, clonal artifacts, expression instability, differentiation defects, and loss of engineered function.
- Drive innovation by identifying technical gaps, improving workflows, and building new capabilities in engineered human stem cell models.
- Communicate technical risks, timelines, decision points, and model readiness clearly through written and oral presentations.
- Maintain high standards for data integrity, reproducibility, documentation, and experimental rigor.