Senior Scientist, Stem Cell-Derived Tissue Models (Contract)
About this role
About the Role Join Amgen’s Predictive Biology team to develop and validate biologically relevant models of human tissue using induced pluripotent stem cell (iPSC) or primary human tissue. A key focus will be validating tissue architecture, cellular composition, differentiation state, maturation, and functional relevance to ensure models are suitable for discovery and translational research. What You'll Do
- Develop human stem cell-derived models that represent tissue biology and enable disease-versus-normal comparisons.
- Differentiate stem cells into diverse tissue-relevant cell types.
- Build complex model systems, including organoids, assembloids, co-cultures, matrix-supported cultures, or other multicellular tissue-like systems.
- Optimize culture conditions, media composition, growth factor cues, extracellular matrix conditions, differentiation timing, and co-culture parameters.
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