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Senior Scientist - Protein Expression

Precision Medicine Group
Houston, TX, USA
On-siteUSD 100,600 - 151,000 / year

About this role

Position Summary

This position will lead protein expression assays on tissues and liquid biopsies (circulating tumor cells, CTCs). Responsibilities include performing assay design and development, validation, and sample testing in a timely manner. Ensures assays are performed according to SOPs and supports development of new procedures and improvement of existing SOPs. Supervises assigned laboratory staff to ensure efficient organization, quality, development, and execution of project(s). Communicating results effectively to clients and develop lasting relationships to support future work.

Essential functions of the job include but are not limited to

  • Leads the development and implementation of protein expression services to support the translational research needs of Precision customers
  • Designs and performs experiments independently, and accurately analyzes and presents data
  • Maintains a high-quality output with the ability to build efficiency into improving productivity metrics
  • Coordinates with management to develop project timelines and deliver on these timelines
  • Trains and mentors junior staff in cell culture and antibody staining techniques, data analysis, collation, and presentation
  • Assists in establishing and improving all procedures and required SOP documentation
  • Responsible for trouble shooting and correcting scientific issues/problems
  • Responsible for ensuring that all experiments are performed on qualified equipment and that use and maintenance logs are up to date when performing experiments
  • Maintains and supports safe lab practices and environment
  • Collaborate with other technical teams in resource sharing and providing technical expertise
  • Monitors project related expenses
  • Serves as a scientific resource to external clients and internal stakeholders
  • Assists with writing reports and presentations for clients as appropriate
  • Supervises assigned project related laboratory staff to ensure quality, development, and execution of project(s).
  • Other duties as assigned

Qualifications

Minimum Required:

  • Ph.D. in cell biology, oncology, or related fields and 6+ years’ relevant laboratory experience OR
  • Master’s Degree and 10+ years’ in an academic core or industry is required

Other required:

  • Experience in cell culture
  • Experience with manual staining and automated protocols (e.g. use of the Leica Bond autostainer) for multiplex Immunofluorescence (mIF) assays
  • Experience with Indica Halo or other digital pathology software
  • Ability to prioritize tasks and function in a team-oriented environment
  • Excellent communication, interpersonal, and organizational skills
  • Must have the ability to organize and analyze data, as well as prepare reports
  • Excellent use of judgment and discretion required
  • Extended work hours may be occasionally necessary in order to meet business demands
  • Ability to lift and carry between 1-15 lbs.; Ability to lift up to 50 lbs. overhead with assistance; frequently required to sit, grasp, and use right/left finger dexterity; May be exposed to a cold freezer environment (Freezer temperatures range between -20ºC -196ºC)
  • Must be able to read, write, speak fluently and comprehend the English language

Preferred:

  • A solid understanding of current GLP and/or ISO/CAP/CLIA standards

  • Experience supervising technical personnel

  • This role is also eligible for a discretionary annual bonus, health insurance, retirement savings benefits, life insurance and disability benefits, parental leave, and paid time off for sick leave and vacation, among other benefits.

  • Reasonable estimate of the current range

  • $100,600—$151,000 USD

  • Candidates must be legally authorized to work in the country of employment without employer sponsorship.

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