Senior Scientist, Manufacturing - Process Development

At Bristol Myers Squibb, our employees often ask, “Who are you working for?”—a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it.

Key Responsibilities

• Provide technical leadership and subject matter expertise for downstream unit operations supporting commercial biologics manufacturing.

• Led tech transfer of commercial and pipeline assets to the Cruiserath facility and wider network, providing technical oversight and recommendations.

• Lead or support process troubleshooting, root cause analysis, investigations and the development of scientifically sound corrective and preventive actions.

• Design, execute and interpret laboratory or scale-down studies that support manufacturing investigations, process understanding and technology transfer.

• Author and review study protocols, technical reports, scientific assessments, regulatory submission content and responses to technical enquiries.

• Drive continuous improvement initiatives that enhance process robustness, efficiency, compliance and knowledge management.

• Collaborate across MS&T, Manufacturing, Quality, Process Development, Analytical, Regulatory and external partner organisations to align technical strategy and execution.

• Evaluate emerging downstream technologies and recommend fit-for-purpose improvements where these could strengthen manufacturing performance.

• Mentor and coach scientists and engineers, supporting effective technical decision-making and the development of downstream capability.

• Technical Scope

The role may support technical studies and manufacturing activities across the following downstream operations:

• Protein chromatography

• Viral inactivation

• Viral filtration

• Ultrafiltration and diafiltration

• Membrane and depth filtration

• Primary recovery and centrifugation

• Process-scale and laboratory-scale downstream equipment, including chromatography and filtration systems

• Required Qualifications and Experience

• Degree in chemical or biochemical engineering, biochemistry, biotechnology or a related scientific discipline.

• Relevant biopharmaceutical industry experience commensurate with the Senior Scientist level. As an initial benchmark: bachelor’s degree with at least 7 years, master’s degree with at least 5 years, or PhD with approximately 2 to 4 years of relevant experience.

• Strong scientific understanding of protein purification, protein stability and downstream process performance.

• Demonstrated experience with downstream processing operations and equipment, including chromatography and ultrafiltration/diafiltration systems.

• Experience supporting commercial manufacturing, process development, technology transfer, validation or manufacturing investigations in a regulated environment.

• Ability to independently analyse complex technical issues, integrate multiple data sources and develop clear, evidence-based recommendations.

• Strong technical writing, presentation and stakeholder communication skills.

• Working knowledge of GMP expectations and the potential manufacturing and regulatory impact of technical decisions.

• Preferred Qualifications

• Experience with process characterisation, scale-down model qualification or continued process verification.

• Experience leading technical transfer activity and support commercial manufacture

• Experience authoring or contributing to CMC documentation and supporting regulatory inspections or technical responses.

• Demonstrated experience mentoring colleagues or providing technical leadership within cross-functional teams.

• Experience applying structured problem-solving, statistical analysis or design of experiments to bioprocess challenges.

• Core Competencies

• Scientific leadership

• Applies deep technical knowledge and sound judgement to complex downstream challenges.

• Execution

• Plans and delivers high-quality technical work with appropriate urgency, rigour and documentation.

• Collaboration

• Builds productive relationships across functions, sites and external partners.

• Communication

• Conveys technical data, risk and recommendations clearly to scientific and non-scientific audiences.

• Problem-solving

• Uses structured, evidence-based approaches to identify root causes and sustainable solutions.

• Coaching

• Shares knowledge, provides constructive guidance and helps build team capability.

• Compliance mindset

• Understands GMP impact and maintains high standards of data integrity and documentation.

• Continuous improvement

• Identifies and implements practical opportunities to improve robustness and efficiency.

• Working Environment and Role Expectations

• Work is performed through a combination of office and laboratory-based activities, subject to site requirements.

• The role requires effective prioritisation across planned studies, manufacturing support and time-sensitive technical issues.

• The successful candidate is expected to work independently while maintaining close alignment with cross-functional stakeholders and site procedures.

• Occasional support outside standard working hours or travel may be required depending on manufacturing and technology transfer needs.

• Why you should apply

• You will help patients in their fight against serious diseases

• You will be part of a company that encourages excellence and innovation, respects diversity, develops leaders and values its employees.

• You’ll get a competitive salary and a great benefits package including, but not only, an annual bonus, pension contribution, family health insurance, 27 days of annual leave, access to BMS Cruiserath on-site gym and life assurance

• We hire for skills and capabilities, not just credentials – if this role excites you, but doesn’t perfectly match your resume, we encourage you to apply anyway.

• How We Work

• Where you work matters – because collaboration, innovation and patient impact happen in many settings. Our roles are structured across four work models: site-essential, site-by-design, field-based and remote-by-design. The model assigned to this role is based on its core responsibilities. Learn more at https://careers.bms.com/ways-of-working.

• Supporting People with Disabilities

• BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [email protected]. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

• Candidate Rights

• BMS will consider qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

• Data Protection

• We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection.

• Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

• If this posting is missing required information required by local law or incorrect, contact BMS at [email protected] with the Job Title and Requisition number. Do not send application-related inquiries to this email. To check your application status, please login to your Candidate Home Account.

• R1607862 : Senior Scientist, Manufacturing - Process Development