About this role
About the Role In this vital role you will focus on advancing programable mRNA design, synthesis, purification, and characterization strategies to enable the discovery and development of next-generation mRNA medicines. You will bring strong expertise in RNA chemistry and nucleic acid therapeutics and will work at the interface of molecular design, analytical characterization, and platform innovation. You will also collaborate across multidisciplinary teams to develop robust RNA technologies that improve therapeutic performance, stability, manufacturability, and translational potential. What You'll Do
- Design and implement high-throughput strategies for modular assembly of mRNA elements to achieve maximal payload expression and programable cellular performance for therapeutic applications.
- Develop and advance mRNA platform technologies, including chemical modification strategies, capping approaches, and sequence/structure optimization.
- Lead experimental efforts to improve RNA quality, purity, stability, and biological activity.
- Develop and apply purification strategies for mRNA, including experience with FPLC-based purification methods where applicable.
- Utilize and interpret analytical methods for mRNA characterization, including HPLC, FPLC, LC-MS, gel electrophoresis, capillary electrophoresis, UV/Vis, and related biochemical and biophysical techniques.
- Evaluate the impact of sequence, structure, chemical modifications, and purification approaches on mRNA performance and developability through functional in vitro. What We're Looking For
- Strong expertise in RNA chemistry and nucleic acid therapeutics.
- Ability to work at the interface of molecular design, analytical characterization, and platform innovation.
- Collaborative, cross-disciplinary team experience.
- Proficiency with analytical methods including HPLC, FPLC, LC-MS, gel electrophoresis, capillary electrophoresis, UV/Vis. Nice to Have Compensation & Benefits
- Salary and benefits information not disclosed in the posting.