About this role
Job title: Senior Research Associate
About the Role Gilead's Protein Therapeutics in Gilead Research invites a Senior Research Associate to join the Protein Sciences team. The successful candidate will be a highly motivated scientist with hands-on knowledge in recombinant antibody purification and protein analytics. Under guidance from the manager, you will work effectively with cross-functional project teams to generate and validate therapeutic proteins and tool molecules, including monoclonal and bispecific antibodies, immunocytokines, and other complex biologics, to support preclinical development across multiple therapeutic areas.
What You'll Do
- Perform protein purification and characterization for quality and document work in electronic lab notebook and various informatics systems to support the preclinical development of biopharmaceutical programs across multiple therapeutic areas.
- Prepare technical reports, summaries, and check in protein samples into the sample bank.
- Use good oral and written communication skills to relay scientific data and update collaborators of purification status and challenges.
- Actively participate in group meetings, present results, interpret data, draw conclusions and propose next steps for the presented work.
- Maintain awareness of cutting-edge technical developments and apply these where possible to improve work quality and efficiency.
What We're Looking For
- Bachelor's degree in Biology, Biochemistry, Chemistry or related field with at least 2+ years of relevant experience; or Master's degree with above-listed characteristics.
- Direct hands-on experience in purifying and characterizing a variety of recombinant proteins, particularly monoclonal antibodies and complex biologics (bi/multi-specific antibodies).
- Hands-on experience in purification techniques including affinity, ion exchange, size exclusion, hydrophobic interaction chromatography using AKTA Avant/Pure.
- Proficiency with analytical protein characterization techniques such as SEC-HPLC or UHPLC, SDS-PAGE or CE-SDS, Endosafe.
- Ability to perform method development and write protocols.
- Strong work ethic and detailed record-keeping.
- Ability to multi-task and work in a fast-paced team environment.
- Familiarity with other protein characterization technologies (DLS, SEC-MALS, LC/MS, IEX/HIC-HPLC).
- Operating experience with automation instruments (autosamplers, automated liquid handling systems) and training/experience in automation system programming or scripting.
- BS in Biology, Biochemistry, Chemistry or related field with at least 2+ years of relevant experience (3+ years preferred) or MS with above-listed characteristics.
Nice to Have
- Strong background in protein sciences and protein biochemistry.
- 2+ years direct experience purifying and characterizing recombinant proteins, especially monoclonal antibodies and complex biologics.
- Hands-on experience with AKTA Avant/PurePro systems.
- Proficiency with additional analytical techniques (DLS, SEC-MALS, LC/MS, IEX/HIC-HPLC).
- Cross-functional collaboration experience.
Compensation & Benefits
- Salary range: USD 94,945.00 - 122,870.00 per year.
- Eligible for discretionary annual bonus and discretionary stock-based long-term incentives (eligibility varies by role).
- Paid time off and a benefits package.
- Benefits include company-sponsored medical, dental, vision, and life insurance plans. Eligible employees may participate in benefit plans, subject to plan terms and conditions.