Senior GxP Engineer, Endpoint Engineer

About the Role

The GxP Endpoint Engineer serves as the primary owner of Moderna’s SCCM environment to support GxP operations, ensuring configurations, deployments, and processes align with QA guidance and compliance. This role builds and maintains a validated, audit-ready SCCM infrastructure that supports operating system deployments, in-place upgrades, patching, and application distribution. The engineer collaborates with Endpoint Engineering, GxP Support, QA, Cloud, Identity, and Lab Engineering teams to drive consistent, compliant endpoint management and creates knowledge base (KB) documentation for support teams. What You'll Do

• Own and manage the SCCM GxP environment, ensuring all configurations, task sequences, and deployments comply with QA guidance and validation standards.

• Design, document, and maintain standard operating procedures (SOPs) and configuration baselines specific to GxP systems.

• Implement and monitor strict QC processes for all deployments, including peer review, QA validation, and change control sign-off prior to production release.

• Oversee all operating system deployments and in-place upgrades (IPU) for validated systems, ensuring consistent execution under GxP change control.

• Manage patching cycles, including Microsoft and third-party updates, coordinating with QA, GxP Support, and Application Owners to plan, validate, and document each phase.

• Create and maintain deployment and compliance reports, providing transparency to QA and management on patch and configuration status across the GxP fleet.

• Collaborate with Application Owners and GxP Support teams to coordinate deployments, validate installations, and resolve environment-specific issues.

• Develop and publish Knowledge Base (KB) articles and operational guides for support teams and end users related to SCCM processes, patching, and imaging.

• Serve as the escalation point for packaging, deployment, and compliance failures impacting GxP systems.

• Partner with QA to participate in audits, provide system validation evidence, and ensure documentation accuracy across all controlled activities.

• Contribute to the ongoing evolution of how SCCM operates in Moderna’s validated environment, helping to design scalable, compliant frameworks for automation and reporting. What We're Looking For

• 6+ years of experience in SCCM/MECM.

• Demonstrated experience owning and managing SCCM in validated GxP environments with QA and change control.

• Knowledge of QA guidance, validation processes, and documentation standards.

• Experience with operating system deployments, in-place upgrades, and patch management (Microsoft and third-party).

• Ability to develop and publish Knowledge Base articles, SOPs, and operational guides.

• Strong collaboration across cross-functional teams including QA, GxP Support, Application Owners, Cloud, Identity, and Lab Engineering.

• Excellent problem-solving, communication, and escalation management in a regulated environment.