Senior Director, Digital & Technology, Portfolio & Financial Management

Senior Director, Digital & Technology, Portfolio & Financial Management at Regeneron

We are seeking a Senior Director to join the Digital & Technology, Commercial and G&A Leadership Team. You will establish the strategy, governance, and operating model for portfolio and financial management while driving investment prioritization, value realization, and organizational effectiveness across the technology portfolio. In addition, you will serve as Chief of Staff to the SVP of Commercial and G&A Digital & Technology, acting as a trusted advisor responsible for leadership planning, communications, and execution of key strategic initiatives. Working closely with senior technology, finance, and business leaders, you will influence major investment decisions and help ensure technology investments deliver measurable business outcomes.

Location and on-site expectations:

• This role can sit on-site in Sleepy Hollow, NY, Rensselaer, NY, or Warren, NJ offices, a minimum of four days per week. Regular attendance for meetings in Sleepy Hollow is required.

What you will do:

• Lead enterprise technology portfolio management across Commercial and G&A Digital & Technology, overseeing intake, prioritization, planning, and investment sequencing based on business value, risk, and delivery capacity.
• Own IT financial management, including budgeting, forecasting, cost transparency, chargeback/allocation models, and technology investment value realization.
• Drive value realization across the Digital & Technology portfolio by developing business cases, defining success metrics, and tracking and reporting realized business value against investment objectives.
• Establish and govern enterprise portfolio and financial management standards, including intake processes, stage-gate reviews, investment frameworks, and governance forums.
• Direct annual and ongoing technology planning cycles, aligning budgets, resource capacity, and prioritization with enterprise strategy and performance objectives.
• Build and mature Technology Business Management (TBM) capabilities, using cost and performance data to improve executive decision-making and demonstrate technology value.
• Lead and develop a high-performing team while improving portfolio predictability, forecast accuracy, resource utilization, cost visibility, and executive reporting.
• Serve as Chief of Staff to the SVP, managing leadership operating rhythms, strategic initiatives, executive communications, stakeholder engagement preparation, standardized executive reporting, AI-enabled portfolio management initiatives, and key vendor relationships.

This role requires:

• BS/BA in Information Systems, Finance, Business, or a related field; MS or MBA preferred.
• 15+ years of progressive leadership across technology portfolio management, PMO, or IT financial management, ideally within a complex, matrixed enterprise.
• Experience with Planview software is a plus.
• Strong command of portfolio and financial management disciplines (platform-agnostic, e.g., PPM/SPM, technology business management, and stage-gate governance frameworks).
• Experience designing and facilitating executive governance forums (e.g., steering committees and investment review boards) and driving decisions among senior stakeholders.
• Experience partnering directly with a senior executive in a chief-of-staff, business-management, or executive-office capacity, including executive communications and board-level preparation, is strongly preferred.
• Ability to operate with a high degree of autonomy and discretion, exercising sound judgment on behalf of senior leadership. Proven ability to influence senior leaders, drive accountability across functional areas, and attract top talent.

Salary and benefits:

• Salary range (annually) from $203,000 to $338,400. Regeneron offers a comprehensive total rewards package which may include bonuses, equity, retirement benefits, health and wellness programs, paid time off, and family support benefits, with specifics varying by country and role.

About Regeneron: Regeneron is a leading biotechnology company dedicated to inventing life-transforming medicines. Our culture emphasizes collaboration and inclusion, and we are committed to equal opportunity in employment without regard to protected characteristics. We provide reasonable accommodations as needed in the recruitment process where required by law.