Senior Clinical Research Associate - Oncology/Myelofibrosis - Central Region

About the Role

Senior Clinical Research Associate (Oncology/Myelofibrosis) will drive site management and quality across ICON's Central Region. You will serve as the primary point of contact between investigational sites and the sponsor, ensuring ICH-GCP compliance, high-quality data, and timely study execution. What You'll Do

• Serve as the primary point of contact between investigational sites and the sponsor

• Conduct all types of site visits, including selection, initiation, routine monitoring, and close-out

• Ensure site compliance with ICH-GCP, SOPs, and regulations

• Maintain up-to-date documentation in CTMS and eTMF systems

• Support and track site staff training and maintain compliance records

• Monitor patient safety, ensuring timely and accurate AE/SAE/PQC reporting

• Support subject recruitment and retention efforts at the site level

• Oversee drug accountability and ensure proper storage, return, or destruction

• Resolve data queries and drive timely, high-quality data entry

• Document site progress and escalate risks or issues to the clinical team

• Assist in tracking site budgets and ensuring timely site payments (as applicable)

• Collaborate with cross-functional partners including CTAs, LTMs, and CTMs

• Travel up to 50% for on-site monitoring visits across the Central region; preference for candidates residing near a major HUB airport What We're Looking For

• Bachelor’s degree in Life Sciences or equivalent, or a qualified RN

• Eligible to work in United States without visa sponsorship

• 3+ years of on-site monitoring experience in the pharmaceutical or CRO industry

• Experience monitoring Oncology trials, specifically Myelofibrosis

• Proficient in ICH-GCP, local regulatory requirements, and clinical systems like CTMS and eTMF

• Clear communicator, problem-solver, and collaborative team player

• Willing and able to travel up to 50% for on-site monitoring visits across the Central region; preference for candidates residing near major HUB airport Nice to Have

• Preference for candidates residing near a major HUB airport to support efficient regional travel Compensation & Benefits

• Competitive salary

• Range of health insurance offerings to suit you and your family’s needs

• Various annual leave entitlements

• Competitive retirement planning offerings

• Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of professionals

• Life assurance

• Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others

• Visit our careers site to read more about the benefits ICON offers.