S2P Process Design & Standards Senior Manager

S2P Process Design & Standards Senior Manager

General Summary:

The Lead, Process Design & Standards is responsible for leading and advancing enterprise Source to Pay (S2P) process design and standards. This role serves as a senior process architect and steward for S2P, helping ensure clarity, consistency, scalability, and alignment with enterprise governance and strategy. Operating within the S2P Center of Excellence, this role focuses on how S2P should work across the organization and partners closely with Category and Sourcing teams, User Orchestration, and Execution Systems & Analytics COE teams to help ensure that process intent is translated into user experiences, systems, and insights—without owning execution, configuration, or operational reporting.

Key Duties and Responsibilities:

• Set the Foundation: Process Architecture & Standards
• Lead the design, documentation, and maintenance of end to end S2P, SRM and Category Strategy process frameworks, standards, policies, controls, and decision models.
• Serve as a senior steward of S2P, SRM and Category Strtategy process integrity, helping drive consistency and scalability across categories, regions, and business units.
• Define clear process decision guidance, handoffs, and control points across sourcing, contracting, buying channels, invoicing, and payment.
• Advance process standards that align with enterprise governance, audit, and compliance expectations in partnership with Finance, Legal, Risk, and Compliance.
• Process Excellence & Optimization
• Apply a market and benchmarking lens to assess S2P, SRM and Category Strategy process maturity and identify improvement opportunities.
• Lead the design, documentation, and maintenance of end to end S2P, SRM, and Category Strategy process frameworks, standards, policies, controls, and decision models.
• Serve as a senior steward of S2P, SRM, and Category Strategy process integrity, helping drive consistency and scalability across categories, regions, and business units.
• Define and maintain process performance measures covering efficiency, effectiveness, compliance, and user experience.
• Lead continuous improvement efforts, leveraging Lean and process excellence methodologies.
• Use performance insights to inform prioritization of process enhancements and future state design decisions.
• Digital & Analytics Alignment
• Advance process standards that are digitally enabled by design and aligned with current and future S2P, SRM and Category Strategy technology roadmaps.
• Partner with the Execution Systems & Analytics COE to translate process standards into system design principles, configuration guardrails, and analytics requirements, without owning system configuration or reporting execution.
• Provide clarity on process intent to support effective solution design, adoption sequencing, and insight generation.
• Cross COE & Enterprise Partnership
• Partner with the User Orchestration COE to ensure process standards are reflected in intake design, buying channel guidance, and decision flows.
• Partner with Category and Sourcing teams to embed enterprise process standards into category strategies and sourcing ways of working.
• Support S2P governance forums with insight into process health, maturity, risks, and improvement priorities.

Knowledge and Skills:

• 7+ years of experience in Procurement, S2P, or Supply Chain process design, optimization, or governance roles.
• Deep expertise in process standardization, controls, and performance management within complex organizations.
• Strong ability to influence outcomes in matrixed, cross functional environments.
• Strong verbal and written communication skills, with the ability to influence and build alignment across cross functional stakeholders.
• Experience developing and maintaining technical and process documentation, including standards, procedures, and decision frameworks.

Education and Experience:

• Bachelor's degree

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At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.

Pay Range: $139,100 - $208,700

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation: On-Site Designated

Flex Eligibility Status:

In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

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Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

About Vertex

Help Us Achieve Our Mission

Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has approved medicines that treat the underlying causes of multiple chronic, life-shortening genetic diseases — cystic fibrosis, sickle cell disease and transfusion-dependent beta thalassemia — and continues to advance clinical and research programs in these diseases. Vertex also has a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases where it has deep insight into causal human biology, including APOL1-mediated kidney disease, acute and neuropathic pain, type 1 diabetes, myotonic dystrophy type 1 and alpha-1 antitrypsin deficiency .

Founded in 1989 in Cambridge, Mass., Vertex's global headquarters is now located in Boston's Innovation District and its international headquarters is in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia, Latin America and the Middle East. Vertex is consistently recognized as one of the industry's top places to work, including 14 consecutive years on Science magazine's Top Employers list and one of Fortune’s 100 Best Companies to Work For. For company updates and to learn more about Vertex's history of innovation, visit www.vrtx.com or follow us on Facebook, Twitter/X , LinkedIn, YouTube and Instagram.

The diversity and authenticity of our people is part of what makes Vertex unique, and we recognize that each employee brings diverse perspectives and strengths. By embracing those strengths and celebrating differences, we are fostering an inclusive culture where each of us can bring our authentic selves to work, inspire innovation together, and change people’s lives.

Our vision is clear: to be the place where an authentic, diverse mix of talent want to come, to stay, and do their best work.

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