Research Specialist A / Laboratory Technician

The laboratory of Dr. Frederick Chris Bennett in the Department of Psychiatry is looking for a research specialist to join our basic neuroscience and immunology laboratory, to study a pediatric neurodegenerative disease and develop novel cell therapies to treat neurodegeneration. This is an excellent opportunity to learn a wide array of in vivo, in vitro, and molecular techniques, contribute to cutting-edge research, and help advance the frontiers of neuroimmunology. The Bennett lab values a supportive and collaborative environment. Former trainees mentored by Dr. Bennett have earned publication authorship and successfully transitioned to graduate/medical schools and industry positions.

The research specialist will work closely senior lab members under the supervision of the principal investigator to perform experiments using a combination of molecular biology, histology, biochemistry, cell biology, as well as mouse breeding and husbandry techniques. Prior experience in cell/tissue culture, flow cytometry, histology, immunofluorescence, confocal or fluorescence microscopy, scientific programming, and mouse handling are desired, but not required. The candidate will be expected to work independently, follow experimental protocols, problem solve, and be open to working in a collaborative manner. Ideal candidates will be able to commit at least two years to the position. Assists and conducts experiments to meet research project objectives. Performs routine duties to ensure smooth operation of the laboratory. Daily management of laboratory tools, documentations, and processes to ensure regulatory compliance and timely completion of project/program deliverables. Closely collaborates with senior lab members on experimental work set ups in accordance to established protocols.

Qualifications

• Bachelor's degree and 0-1 year of experience or equivalent combination of education and experience required.

• CONTINGENT UPON GRANT FUNDING.

• Job Location - City, State

• Philadelphia, Pennsylvania

Responsibility Breakdown:

• Perform in vivo experiments, ranging from cellular transplantation, tissue sample collection, dissection, and cell isolation

• Conduct experiments to interrogate gene and protein expression, including by immunostaining, microscopy, flow cytometry, RNAscope, and RNAseq

• Maintain sterile in vitro cell culture practices and perform cell sorting by FACS

• Genetic engineering using molecular cloning techniques (DNA preparation, PCR, ligation, and transformation), CRISPR/Cas9

• Manage mouse colony, including breeding and genotyping

• Prepare stock solutions, aliquot reagents, monitor supplies, autoclave solutions, and maintain biosafety compliance records

• Contribute to general laboratory organization and inventories (as part of a team doing this)

• Keep detailed records of experimental work in a lab notebook

• Analyze flow cytometry, and imaging data

• Represent analyzed data in the form of figures

• Participate in lab journal club and present research progress in lab meetings

• Department / School

• Perelman School of Medicine

• Pay Range

• $45,278.00 - $50,000.00 Annual Rate

• Equal Opportunity Statement

• The University of Pennsylvania is an equal opportunity employer. Candidates are considered for employment without regard to race, color, sex, sexual orientation, religion, creed, national origin (including shared ancestry or ethnic characteristics), citizenship status, age, disability, veteran status or any class protected under applicable federal, state or local law.

• Special Requirements

• Background checks may be required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.

• University Benefits

• Health, Life, and Flexible Spending Accounts: Penn offers comprehensive medical, prescription, behavioral health, dental, vision, and life insurance benefits to protect you and your family’s health and welfare. You can also use flexible spending accounts to pay for eligible health care and dependent care expenses with pre-tax dollars. Tuition: Take advantage of Penn's exceptional tuition benefits. You, your spouse, and your dependent children can get tuition assistance here at Penn. Your dependent children are also eligible for tuition assistance at other institutions. Retirement: Penn offers generous retirement plans to help you save for your future. Penn’s Basic, Matching, and Supplemental retirement plans allow you to save for retirement on a pre-tax or Roth basis. Choose from a wide variety of investment options through TIAA and Vanguard. Time Away from Work: Penn provides you with a substantial amount of time away from work during the course of the year. This allows you to relax, take vacations, attend to personal affairs, recover from illness or injury, spend time with family—whatever your personal needs may be. Long-Term Care Insurance: In partnership with Genworth Financial, Penn offers faculty and staff (and your eligible family members) long-term care insurance to help you cover some of the costs of long-term care services received at home, in the community or in a nursing facility. If you apply when you’re newly hired, you won’t have to provide proof of good health or be subject to underwriting requirements. Eligible family members must always provide proof of good health and are subject to underwriting. Wellness and Work-life Resources: Penn is committed to supporting our faculty and staff as they balance the competing demands of work and personal life. That’s why we offer a wide variety of programs and resources to help you care for your health, your family, and your work-life balance. Professional and Personal Development: Penn provides an array of resources to help you advance yourself personally and professionally. University Resources: As a member of the Penn community, you have access to a wide range of University resources as well as cultural and recreational activities. Take advantage of the University’s libraries and athletic facilities, or visit our arboretum and art galleries. There’s always something going on at Penn, whether it’s a new exhibit at the Penn Museum, the latest music or theater presentation at the Annenberg Center, or the Penn Relays at Franklin Field to name just a few examples. As a member of the Penn community, you’re right in the middle of the excitement—and you and your family can enjoy many of these activities for free. Discounts and Special Services: From arts and entertainment to transportation and mortgages, you'll find great deals for University faculty and staff. Not only do Penn arts and cultural centers and museums offer free and discounted admission and memberships to faculty and staff. You can also enjoy substantial savings on other goods and services such as new cars from Ford and General Motors, cellular phone service plans, movie tickets, and admission to theme parks. Flexible Work Hours: Flexible work options offer creative approaches