About this role
Principal Scientist, Neuroscience / Genetic Medicine
Locations: Tarrytown Time type: Full time Posted Yesterday Job requisition id: R50139
Build our future together: At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Principal Scientist to join our Genetic Medicines team, helping advance the preclinical development of targeted genetic medicines for disorders of the central nervous system. In this role, you will design and lead experiments across CNS disease models, working as part of a collaborative, multidisciplinary team spanning platform technology, disease biology, and early clinical development.
This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.
When & where: Location: Tarrytown, NY Work model/flexibility: Onsite
Discover your role:
- Design experiments to evaluate the efficacy, target engagement, and delivery efficiency of viral and non-viral therapeutic candidates across CNS disease models
- Design AAV transgene cassettes to optimize therapeutic efficacy
- Lead a team of associates in the execution of experiments and analysis of primary data
- Interpret complex datasets, integrating findings with current scientific literature to propose data-driven next steps
- Communicate project strategy, scientific vision, and data updates to senior leaders
- Author and review preclinical study reports to support regulatory submissions
- Approach scientific problems with an engineering mindset and a design-build-test-learn framework
- Coach and mentor junior scientists within a multidisciplinary team environment
This role requires:
- Experience evaluating DNA- or RNA-based therapeutics in small-animal models
- Hands-on experience with molecular biology techniques
- Experience mentoring and managing research associates
- Excellent communication and presentation skills
- Preferred: Ph.D. in neuroscience, gene therapy, or a related discipline
- Preferred: 5+ years of combined postdoctoral and industry experience in biotechnology, genetic medicines, or CNS drug discovery
- Preferred: knowledge of both viral and non-viral genetic medicine delivery modalities
Salary Range (annually) $128,600.00 - $210,000.00
About Us Regeneron is a leading biotechnology company that invents life-transforming medicines for people with serious diseases. Founded and led for over 30 years by physician-scientists, our unique ability to repeatedly and consistently translate science into medicine has led to nine FDA-approved treatments and numerous product candidates in development, almost all of which were homegrown in our laboratories. Our medicines and pipeline are designed to help patients with eye diseases, allergic and inflammatory diseases, cancer, cardiovascular and metabolic diseases, neurology, infectious diseases and rare diseases.
Regeneron is also proud of award winning culture of innovation, being recognized as a Great Place to Work in 2021, Fast Company’s Best Workplace for Innovators in 2020, and Forbes JUST companies in 2020, among others.