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Principal Scientist – Lead Discovery and Targeted Protein Degradation Biochemistry

Amgen
onsite
Thousand Oaks, CA, United States

About this role

Job title: Principal Scientist – Lead Discovery and Targeted Protein Degradation Biochemistry

About the Role Lead discovery programs focused on protein biochemistry and targeted protein degradation. Responsible for protein production, assay development, and mechanistic characterization to enable discovery and advancement of novel small-molecule therapeutics, while leading a small team of scientists.

What You'll Do

  • Lead protein expression, purification, and characterization strategies for challenging proteins to enable discovery of novel small-molecule therapeutics.
  • Develop and implement biochemical and biophysical assays to support hit identification, validation, optimization, and mechanism-of-action studies.

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