Principal Research Scientist I

Principal Research Scientist I

Job Description

Purpose

We are seeking a highly-motivated toxicologist to support discovery-stage programs across therapeutic areas within preclinical safety. As part of the Investigative Toxicology and Pathology group, the successful candidate will effectively leverage in silico, in vitro, and in vivo tools to design and execute a safety assessment strategy to support pipeline advancement. As project toxicologist, this scientist will work cross-functionally, providing critical subject matter expertise and data integration to drive progress for programs.

Responsibilities

• Support project teams to design and execute a safety strategy specific to the needs of the project by leveraging internal and external resources, in silico tools, in vitro models, and in vivo studies. Select and design experiments that answer key questions, are decision-enabling, and promote judicious progression of programs.
• Support development and deployment of in vitro tools for safety assessment (simple and complex in vitro models, or NAMs) and utilize appropriate endpoints (imaging, toxicogenomic, etc) to support decision-making.
• Demonstrate the ability to identify and resolve key project hurdles by effectively utilizing available information and resources.
• Communicate effectively across cross-functional teams and with leadership to support alignment on program strategy.
• Proactively seek out new information in the literature and incorporate this into individual projects as well as the overall safety assessment strategy.
• Seize opportunities to pursue project-relevant exploration and experiments to support data-driven decision-making and program progress.
• May mentor/supervise a team of one or more and evaluate the performance of those individuals; accountable for the effective performance of the team/individuals.
• Collaborate effectively with other teams to identify areas of scientific advancement and efficiency.

Qualifications

Required:

• Bachelor’s Degree or equivalent education and extensive, typically 14+ years of experience, Master’s Degree or equivalent education and typically 12 years of experience, PhD and typically 6+ years of experience.
• Experience directing the use of, and interpreting data from, in vitro safety studies.
• Demonstrate ability to function independently, generating original research or development strategies.
• Possess thorough theoretical and practical understanding of own scientific discipline.
• Effective writer and communicator of research. Demonstrated scientific communication and presentation skills.

Preferred:

• People leadership and management experience

• DABT board certification or equivalent

• Experience working on cross-functional project teams, including but not limited to, within pharmaceutical development

• Additional Information

• Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more in the posted range. This range may be modified in the future.

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.

• This job is eligible to participate in our long-term incentive programs.

• Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

• AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

• US & Puerto Rico only - to learn more, visit US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

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• Pay Range: 124500 - 236500 USD

• Where We Work

• Role is exclusively performed at a site or office and onsite presence is required. Employees who are site/office-based and can occasionally perform their role virtually work both in the office and remotely, following the policies and regulations in place at their location. US Employees must be in the office on Tuesday, Wednesday, and Thursday with flexibility to work remotely on Mondays and Fridays. Three days in the office is the minimum; some individuals or teams may require more in-office days due to meetings, business/project needs or their role.