About this role
Job title: Precision Medicine Global Biomarker Lead - Rare Disease
About the Role The Global Biomarker Lead in Precision Medicine will be a key member of Amgen’s cross-functional product teams, driving clinically robust biomarker strategies for Rare Disease programs and aligning with global development goals. The role includes assay readiness, vendor management, and translating biomarker data into actionable insights for clinical development, research, and medical affairs.
What You'll Do
- Lead development and execution of program-specific clinical biomarker strategies to inform target engagement, pharmacodynamics, mechanism of action, and patient selection across early and late-stage programs
- Serve as precision medicine subject matter expert within product evidence generation teams to deliver translational approaches and high-quality biomarker datasets
- Oversee biomarker elements in clinical protocols, biomarker analysis plans, regulatory submissions, investigator meetings, advisory boards and publications
- Lead and partner with biomarker sub-teams to plan all components of strategy implementation including vendor evaluations, budget/contract planning, biomarker and pharmacodynamic sample operations, data analysis plans, and cross-functional data sharing
- Interpret and communicate key clinical biomarker findings to cross-functional and non-technical stakeholders, including Precision Medicine teams, product teams, R&D leadership, external scientific congresses, and lay audiences
- Establish biomarker studies and collaborations with academic laboratories/KOLs
What We're Looking For
- Doctorate degree in a bioscience or medical discipline and 3+ years of industry experience OR Master’s degree in a bioscience or medical discipline and 6+ years of industry experience OR Bachelor’s degree in a bioscience or medical discipline and 8+ years of industry experience
- PhD in a relevant field; PharmD, MD, or equivalent considered
- Minimum 5+ years of relevant experience in industry
- Experience in developing program-based clinical biomarker strategies and execution while supporting cross-functional clinical study teams
- Strong expertise in rare disease, autoimmunity, inflammation, cell biology, and genomics
- Strong written and verbal communication with experience drafting technical reports, clinical documents, and biomarker publications, and interpreting biomarker results to leadership
- Experience implementing biomarker platforms and technologies including biomarker assay development, analysis of clinical samples, and managing biomarker assay outsourcing with external vendors/CROs
- Experience managing direct and dotted line reports and matrix management of staff
- Experience working in globally dispersed teams and with global programs; regulatory filings is a plus
- Poise and professionalism with strong communication and influencing skills
Nice to Have
- Additional preference for PhD in a relevant field; PharmD, MD, or equivalent considered
- Experience with a broad array of biomarker platforms and technologies beyond core assays
- Demonstrated ability to establish partnerships with academic laboratories and KOLs
- Experience with cross-cultural collaboration and global program execution
Compensation & Benefits
- The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted; actual salary will vary based on skills, experience, and qualifications
- Amgen Total Rewards Plan includes health and welfare benefits, group medical/dental/vision, retirement savings with company contributions, work-life balance support, and career development opportunities