About this role
About the Role The Beck Lab at The Jackson Laboratory for Genomic Medicine and University of Connecticut Health Center seeks a postdoctoral fellow to study the mechanisms and consequences of structural variants across human and mammalian genomes. The role combines computational analysis of existing genomic and transcriptomic data with hands-on laboratory experiments, including cell culture and iPSC work. The successful candidate will lead projects, develop analyses, and prepare results for publication.
What You'll Do
- Conduct cell culture, molecular biology and biochemistry experiments
- Maintain lab equipment, reagents, and follow safety protocols
- Author manuscripts and grant applications
- Present results at lectures and conferences
- Use bioinformatics tools to analyze genomic and transcriptomic data from human and mouse samples
- Interpret variation, variant mechanisms, and the effect of variants on transcription
- Contribute to project planning and implementation
- Perform data curation and maintain documentation
- Generate reproducible analysis and properly use statistics to support observations
- Collaborate with a multidisciplinary team of researchers who perform bench and computational experiments
What We're Looking For
- PhD in Physiology, Molecular Biology, Genetics, Biomedical Engineering, or a related field
- Strong publication record in peer-reviewed journals
- Excellent communication and teamwork skills, with the ability to work independently and collaboratively
- Experience using statistical inference to support results
- Fluency with multiple experimental techniques coupled with ability or willingness to learn Python or R and common bioinformatics tools
- Experience with cell culture, and in particular iPSCs, will be beneficial for these projects
Nice to Have
- Experience with iPSC culture and differentiation
- Knowledge of structural variation and variant mechanisms
- Experience using computational libraries for tabular data and statistical analysis
- Experience executing jobs and pipelines in a high-performance computing cluster
- Experience working in a Linux command-line environment
Compensation & Benefits
- JAX Salary: Year 0-1: $65,589; Year 1-2: $67,318; Year 2-3: $69,095; Year 3-4: $70,521; Year 4-5: $72,877; Year 5-6: $75,569
- Based on years of experience as Postdoc