PK/PD Principal Scientist

Job title: PK/PD Principal Scientist

About the Role Zoetis seeks a PK/PD Principal Scientist to join our Veterinary Medicine Research and Development PK/PD Scientist Team. The role will design, conduct, analyze, and interpret in vivo PK/PD studies across multiple species, supporting projects from early research through late-stage development. The successful candidate will be a highly motivated, independent leader who can effectively collaborate with other team members to advance programs.

What You'll Do

• Independently design and analyze in vivo PK/PD, PK and TK studies in multiple veterinary species, including writing study protocols and reports.
• Provide PK and PK/PD modeling and simulation to help select lead candidates and optimize dose regimens.
• Collaborate with bioanalytical team to assess suitability of analytical assays and forecast analytical requirements for projects.
• Lead development of scientific strategy across therapeutic areas with a focus on mechanistic platforms/biomarkers to aid translation, measurement of target engagement, and dose regimen predictions.
• Work collaboratively and communicate effectively with multidisciplinary teams to design and prosecute studies in line with the strategic direction of the project.
• Present research results to scientific teams, management, and regulatory agencies.
• Write sections of regulatory submissions, respond to inquiries from regulatory agencies, and maintain knowledge of regulatory guidance documents.

What We're Looking For

• Ph.D in pharmacology, biochemistry, or related field with 4 or more years of relevant pharmaceutical development experience.
• DVM DACVCP or DVM Dipl. ECVPT is highly desirable.
• Proven ability to design, analyze and interpret in vivo PK and PK/PD studies.
• Experience with biotherapeutics (protein therapeutics) highly desirable.
• Proficient in PK and PK/PD analysis software such as WinNonlin, Monolix or Watson.
• Excellent verbal and written communication skills.
• Self-starter, able to prioritize work and work efficiently with minimal supervision.
• Working knowledge of bioanalytical methodology.
• Knowledge of ADA assays and assessment of immunogenicity of biotherapeutics highly desirable.
• Experience in PK/PD modeling and simulation such as PBPK, QSP or population PK modeling using NONMEM, R, or related software highly desirable.
• Experience interacting with regulatory agencies highly desirable.
• Experience conducting GLP studies desirable.

Nice to Have

• DVM DACVCP or DVM Dipl. ECVPT (preferred).
• Experience with regulatory submissions or direct interactions with regulatory agencies.
• Additional experience with GLP studies.

Compensation & Benefits

• Salary: USD 114,000 - 185,000 per year.
• This position is eligible for short-term incentive compensation and long-term incentives.
• Zoetis offers comprehensive benefits including healthcare and insurance beginning day one, a 401K match and profit-sharing, and 4 weeks of vacation.