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Manager, R&D Business Operations

ICON
Remote
Remote

About this role

Manager, R&D Business Operations

At ICON Strategic Solutions, you will work in a sponsor-dedicated model, supported by ICON’s global expertise.

As the world’s largest FSP organisation, with over 90 sponsor partnerships, we offer stability, career development and a collaborative environment where your work contributes to the development of treatments that benefit patients worldwide.

The Manager, R&D Business Operations provides operational and analytical support to R&D business functions, with primary responsibility for the creation, generation, and management of purchase orders following contract execution

What You Will Do:

The Manager works independently in managing purchase order workflows and system processes, operating with moderate autonomy while escalating complex financial, compliance, or risk-related matters as appropriate.

Key responsibilities include:

  • Create, generate, and manage purchase orders in Ariba/SAP following full contract execution, ensuring alignment with contract terms, budgets, and approved scopes of work in compliance with company policies and service level standard turnaround times.
  • Translate contractual payment terms, milestones, and fee structures into accurate and compliant purchase order structures.
  • Review executed agreements to ensure proper financial setup, including funding allocations, payment schedules, and budget tracking.
  • Process and manage change orders, PO amendments, closures, and funding adjustments in accordance with contract modifications.
  • Partner with R&D, Finance, and Strategic Sourcing to ensure timely PO issuance and resolution of system or budget discrepancies.
  • Monitor purchase order lifecycle activities, including invoice matching, goods receipt confirmations, accrual support, and PO reconciliation.
  • Ensure compliance with internal financial controls, delegation of authority policies, and procurement procedures prior to PO release.
  • Serve as system subject matter expert (SME) for Ariba/SAP purchase order workflows and provide guidance to internal stakeholders.
  • Train business partners on purchase requisition and PO processes, including proper documentation and system requirements.
  • Facilitate weekly or monthly operational status meetings related to PO issuance, budget tracking, and financial metrics as appropriate.
  • Generate reports and dashboards to track PO cycle times, open commitments, spend against budget, and operational KPIs.
  • Support month-end and year-end close activities, including accrual validation and financial reconciliation.

Your Profile:

Required qualifications and experience:

  • Bachelor’s degree required; advanced degree preferred.
  • Minimum 5 years of experience in pharmaceutical/biotech business operations, procurement operations, finance operations, or contract-to-PO management.
  • Demonstrated experience creating and managing purchase orders within enterprise systems (e.g., SAP, Ariba).
  • Strong understanding of procure-to-pay (P2P) processes, including requisitioning, PO generation, invoice matching, and accruals.
  • Experience working cross-functionally with R&D, Finance, Strategic Sourcing, Legal, and Accounts Payable.
  • Strong analytical skills with the ability to interpret contract financial terms and translate them into operational system requirements.
  • Working knowledge of pharmaceutical/biotech regulatory and compliance considerations impacting vendor payments and financial controls.
  • Ability to identify financial discrepancies or operational risks and escalate appropriately.
  • Strong organizational skills with the ability to manage multiple purchase orders, vendors, and deadlines simultaneously.

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