About this role
About the Role Join NIBR Oncology as an in vivo scientist in Cambridge, MA to lead design and execution of in vivo anti-tumor efficacy and PK/PD studies across CDX, PDX, and syngeneic models. Develop novel in vivo assays and generate translational data to inform early-stage clinical development. This labhead-based role requires leadership of associate scientists and collaboration across multidisciplinary teams. What You'll Do
- Design pre-clinical in vivo studies to explore novel hypotheses, screen candidate molecules, and establish proof-of-concept of new modalities
- Develop in vivo CDX, PDX, and syngeneic models to evaluate anti-tumor activity, PK/PD relationships, relevant biomarkers, and key translational questions
- Manage associate-level scientists
- Collaborate with cross-functional project teams
- Critically analyze and present results within a multidisciplinary team environment
- Ensure careful adherence to animal protocols and proper documentation of data and methods in electronic laboratory notebook What We're Looking For
- PhD with 5-8 years of research experience as a postdoc or in the pharmaceutical/biotech industry
- Deep knowledge of antibody drug conjugates
- Extensive experience working with CDX and PDX xenograft tumor models and/or syngeneic models
- Expertise in cell culture, PCR, ELISA, Western blot, and flow cytometry
- Strong analytical, communication (written and verbal), and organizational skills, including proficiency with PowerPoint and commonly used data analysis programs such as Prism and Excel Nice to Have
- A strong background and expertise in antibody drug conjugates is preferred Compensation & Benefits
- Salary range: $126,000 - $234,000 per year
- Novartis Compensation and Benefit Summary applies; final salary determined by skills and experience and reviewed periodically after joining