Head of Translational Medicine

About the Role Moderna is seeking an enterprise-minded Head of Translational Medicine to lead and integrate translational medicine, translational research, and clinical pharmacology & pharmacometrics into a unified, high-impact organization. The role will define and execute a cohesive translational strategy across Moderna’s oncology and therapeutics pipeline—from discovery through clinical development and lifecycle management—and lead a large, multidisciplinary team to accelerate decision-making and maximize the probability of technical and regulatory success. What You'll Do

• Define and lead an integrated, end-to-end translational strategy across Translational Medicine, Translational Research, and Clinical Pharmacology/Pharmacometrics, spanning discovery through lifecycle management
• Establish a unified framework connecting biological insights, biomarkers, and quantitative pharmacology to enable rapid, data-driven decision-making
• Ensure alignment of translational strategies with program and portfolio objectives, including development pathways, target product profiles, and regulatory strategies
• Lead translational input into governance, ensuring rigorous, data-driven go/no-go decisions across the pipeline
• Lead and unify a high-performing, multidisciplinary translational organization, connecting scientific, clinical, and quantitative capabilities into a cohesive model
• Represent Moderna’s translational strategy externally, engaging regulators, scientific leaders, and partners to shape scientific direction and advance best-in-class approaches across the portfolio
• Lead execution of early clinical translational plans, including biomarker implementation, endpoint operationalization, and data interpretation to enable clear proof-of-concept decisions
• Partner with clinical development to translate scientific hypotheses into actionable clinical plans What We're Looking For
• Proven ability to lead and unify translational disciplines across discovery through lifecycle management in oncology/therapeutics
• Strong track record in biomarker strategies, quantitative pharmacology, and data-driven decision-making
• Experience influencing strategy, prioritization, and execution across R&D leadership; ability to engage regulators and external partners
• Excellent cross-functional leadership and governance experience; strategic thinker who can shape development pathways and regulatory strategies