Faculty Position in Induced Pluripotent Stem Cell (iPSC) Modeling in Neurodegenerative Diseases

Position Title: Faculty Position in Induced Pluripotent Stem Cell (iPSC) Modeling in Neurodegenerative Diseases

Position Summary: The Neuroscience Research Center at the Medical College of Wisconsin invites applications for a tenure track Assistant Professor position in induced pluripotent stem cell (iPSC) based modeling of neurodegenerative diseases, with a particular emphasis on Alzheimer’s disease and related disorders. We seek a highly motivated scientist who will establish an innovative, independent research program leveraging iPSCs to investigate mechanisms of neurodegeneration, cellular vulnerability, and therapeutic discovery. Candidates using approaches such as single cell genomics, organoid systems, CRISPR engineering, or cell type–specific functional assays are especially encouraged to apply.

Position Highlights:

• Develop and sustain a rigorous, externally funded research program centered on iPSC‑based models of neurodegenerative disorders.
• Mentor PhD students, including supervision of thesis research, career development, and scientific training.
• Contribute to graduate‑level and medical‑student education in neuroscience, stem cell biology, neurodegeneration, or related fields.
• Participate in interdisciplinary initiatives across neuroscience, neurology, genetics, and translational research programs.
• Engage in departmental, institutional, and professional service activities.

About the Neuroscience Research Center: The Medical College of Wisconsin's Neuroscience Research Center (NRC), part of the Wisconsin Institute for NeuroScience (WINS), is a catalyst for advancing new, cutting-edge research strategies to prevent and treat neurological disorders. We strive to enhance basic and translational neuroscience at MCW through the development of an MCW-wide programmatic plan. By integrating with MCW’s other key departments, as well as leading neuroscientists throughout Milwaukee and beyond, the NRC emphasizes the importance of collaborative neuroscience research to strengthen and differentiate clinical care at MCW and its affiliates. By fostering collaboration and engaging different perspectives, we unlock the potential to imagine boundless possibilities.

Qualifications

Required:

• PhD and postdoctoral training in neuroscience, stem cell biology, neurodegeneration, or a closely related field.
• Demonstrate expertise in iPSC derivation, differentiation, organoid modeling, or disease-mechanism studies.
• Strong written and oral communication skills, including a record of peer-reviewed publications reflecting creativity and scientific rigor.
• Evidence of potential to secure extramural funding (NIH, NSF, foundation, or equivalent).
• Commitment to mentoring, creating an inclusive training environment, and demonstrating excellence in teaching.
• Ability to work effectively both independently and in a collaborative cross-disciplinary environment
• Eligibility for a faculty appointment at the Medical College of Wisconsin.

Preferred:

• Experience modeling Alzheimer’s disease or related disorders using iPSC‑derived neurons, astrocytes, microglia, or mixed‑cell systems.

• Expertise in single‑cell transcriptomics, proteomics, high‑content imaging, or computational analysis.

• Demonstrated ability to collaborate across basic, translational, and clinical research teams.

• The Medical College of Wisconsin is an Equal Opportunity Employer. We are committed to fostering an inclusive community of outstanding faculty, staff, and students, as well as ensuring equal educational opportunity, employment, and access to services, programs, and activities, without regard to an individual's race, color, national origin, religion, age, disability, sex, gender identity/expression, sexual orientation, marital status, pregnancy, predisposing genetic characteristic, or military status. Employees, students, applicants or other members of the MCW community (including but not limited to vendors, visitors, and guests) may not be subjected to harassment that is prohibited by law or treated adversely or retaliated against based upon a protected characteristic.

• Milwaukee, the largest city in Wisconsin, is located on Lake Michigan’s western shore. A metropolitan area with more than 1.6 million people, Milwaukee is an affordable, comfortable place to live, work, and play, big enough to be exciting and uncongested enough to get around easily. Milwaukee’s many neighborhoods have incredible charm, accommodating a variety of lifestyles, from high-rise apartments to small farms. Nestled along a magnificent bluff overlooking Lake Michigan, Milwaukee’s downtown is home to botanical gardens, lakefront museums, a theater district, the world champion Milwaukee Bucks, the Milwaukee Brewers, bustling nightlife, and award-winning restaurants. The lake and its harbors are skirted by scenic parklands and provide first-class opportunities for recreation, including hiking, cycling, boating, and more. Milwaukee has all the advantages of a large, vibrant city but without the stress or cost.