Director-level Scientist

Columbia University

Sulzberger Columbia Genome Center (CGC) is seeking a director-level scientist to lead its efforts to integrate genomics and clinical research in collaboration with the Herbert Irving Comprehensive Cancer Center (HICCC). This position would work jointly with HICCC, CGC, and the Biomedical Informatics Resource to facilitate cellular and molecular analysis of clinical trial specimens via multi-modal genomics (including bulk, single-cell, and spatial profiling) and integration with clinical data stored in electronic health records. These efforts require coordination between the physician-scientists leading clinical trials and scientists in CGC and clinical informatics to identify biological and clinical questions, link these to the appropriate experimental and analytical approaches, and organize clinical studies. In some cases, these studies may also involve the analysis of patient-derived models from clinical specimens (e.g. organoids, explants, xenografts) or other pre-clinical studies.

Position Summary

30%: Developing and designing translational studies that leverage genomic analysis of clinical trial specimens.

30%: Coordinating the collection of genomic and clinical informatics data from clinical trials.

40%: Leading the integration of genomic and clinical datasets to develop new insights into patient responses in clinical trials.

Responsibilities

• 30%: Developing and designing translational studies that leverage genomic analysis of clinical trial specimens.
• 30%: Coordinating the collection of genomic and clinical informatics data from clinical trials.
• 40%: Leading the integration of genomic and clinical datasets to develop new insights into patient responses in clinical trials.

Minimum Qualifications

• PhD in biology, chemistry, genomics, systems biology, bioengineering, or a related field.
• 5 years of experience required

Preferred Qualifications

• Experience with experimental and computational genomics, including bulk, single-cell, and spatial profiling.
• Experience with electronic health records and clinical informatics.
• Specific expertise in basic and translational cancer research, including animal and patient-derived models (in vivo and in vitro).
• Experience with data science and statistics, including integration of genomic and clinical data.
• Experience in scientific writing, including peer-reviewed publications, grant proposals, and collaborative research applications.

Other Requirements

• N/A

Equal Opportunity Employer / Disability / Veteran

Columbia University is committed to the hiring of qualified local residents.