Director, Degrader Chemistry

Director, Degrader Chemistry

Cambridge, US | full time | Job ID: 11672

The ideal candidate will work in a highly collaborative and cross-functional team to develop antibody drug conjugates (ADCs). The position requires close collaborations with various functional teams, outside partners, CROs, and CDMOs.

Your contribution

• Participate in ADC research and development programs by providing chemistry know-how and expertise in protein degraders, molecular glues, payloads, and linkers.
• Design and synthesize protein degraders and molecular glues
• Coordinate and collaborate with CMC team supporting process development and GMP manufacturing
• Prepare preclinical documents for IND filing
• Work cross-functionally within the R&D organization
• Collaborate with outside partners, CROs, and CDMOs

A good match

• Ph.D. or M.S. in organic chemistry or a related discipline with 8 plus years of industry experience in drug discovery and development
• Strong experience in protein degraders and molecular glues
• Proven track record of creative thinking and consistent delivery as demonstrated by publication/presentation records
• Highly organized with a proactive mentality
• Thrive in a team center and collaborative environment
• Excellent interpersonal, networking, and communication skills

Preferred Requirements: Experience in ADC payload, linker, and conjugation chemistry, experience in ADC manufacturing process development.

Your benefits and remuneration:

• Expected Pay Range: $168,100/year to $268,700/year + benefits, annual bonus & equity (bonus and equity is variable and dependent on company and individual performance). Compensation for the role will depend on several factors, including responsibilities of the job, education, experience, knowledge, skills, and abilities.

BioNTech US is committed to employee wellbeing and offers best-in-class benefits & HR programs to support an inclusive & diverse workforce. Salaried/Position-Targeted Hourly Employees working 30+ hours per week are eligible for our comprehensive benefits package. Benefits include but are not limited to:

• Medical, Dental and Vision Insurance
• Life, AD&D, Critical Illness Insurance
• Pre-tax HSA & FSA, DCRA Spending Accounts
• Employee Assistance & Concierge Program (EAP) available 24/7
• Parental and Childbirth Leave & Family Planning Assistance
• Sitterstream: Virtual Tutoring & Childcare Membership
• Paid Tim