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Customer Success Manager- Strategic

SOPHiA GENETICS
Remote (United States) Posted Oct 28, 2026
Full-timeRemote

About this role

SOPHiA GENETICS is a leader in data-driven medicine, and our clients (hospitals, clinical labs, and research and biopharma organizations) rely on the SOPHiA DDM platform to advance precision medicine. As a Client Success Manager- Strategic, you own the long-term commercial and strategic relationship with a portfolio of strategic clients across the full lifecycle, from onboarding through renewal and expansion.

This is a strategic, consultative, growth-oriented role. You are not a reactive support function. You will act as a trusted partner to lab directors, clinicians, and senior stakeholders, leading engagement like a project manager, identifying growth opportunities, and turning satisfied clients into vocal advocates for SOPHiA in the industry.

Own the client lifecycle for our strategic accounts in the USA

  • Lead onboarding, adoption, and value realization plans for each client, with clear milestones and success criteria.

  • Run structured business reviews with client leadership to review outcomes, align on priorities, and shape the roadmap together.

  • Coordinate cross-functional resources (Support, Product, Bioinformatics, Sales, Marketing) to deliver on client commitments. Drive retention and utilization

  • Own renewal outcomes and proactively manage risk, using usage data and health indicators to act before issues escalate.

  • Identify and close adoption gaps by driving platform usage, new workflows, and additional applications within existing accounts.

  • Build and execute account plans with defined utilization and retention targets. Grow your accounts

  • Uncover expansion opportunities (new applications, additional sites, higher volumes, new teams) through consultative discovery.

  • Partner with Sales to develop and close upsell and cross-sell opportunities and contribute to forecasting and pipeline accuracy.

  • Build business cases that connect SOPHiA DDM to the client's clinical, operational, and financial goals. Create champions

  • Deliver an exceptional client experience, measured through satisfaction, NPS, and long-term loyalty.

  • Develop advocates who will serve as references, case study subjects, speakers, and advisory board members.

  • Gather client voice and feed insights back to Product and leadership to influence what we build.

Requirements

  • 7-10+ years in client success, account management, consulting, or project management, ideally in life sciences, healthcare, diagnostics, genomics, or SaaS.

  • A proven record of improving retention and driving expansion revenue, with measurable results you can speak to.

  • Strong project and program management skills, with the ability to run multiple complex engagements at once.

  • Commercial acumen: you are comfortable with renewals, pricing and contract discussions, and building a business case.

  • Excellent communication and executive presence, with credibility in conversations with scientific, clinical, and operational leaders.

  • A data-driven mindset, comfortable using usage and health metrics to guide decisions.

  • Familiarity with genomics, NGS workflows, or bioinformatics is a strong plus.

  • Fluency in English

  • Willingness to travel 30-40% to visit clients accross USA and attend industry events.

Benefits

  • Outstanding Medical (with Telemedicine), Dental, and Vision Plan with 90% employer contributions.
  • Life and AD&D company provided
  • Company 4% match 401K contributions
  • Company-paid short and long-term disability insurance
  • 20 Days PTO (Increasing to 25 with Tenure), 5 sick days and 14 public holidays recognised
  • FSA commuter benefits
  • Supplemental employee insurance options are available for accident, critical Illness, hospital and legal
  • Voluntary pet, auto and home insurance options
  • Employer Assistance Program free for all employees

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