Clinical Trial Manager

About the Role ICON Real World Solutions Team is seeking an experienced Clinical Trial Manager to oversee the end-to-end operational delivery of assigned clinical trials. You will ensure delivery against timelines, budget, and quality, including oversight of site management (remote and onsite), clinical team activities, and regulatory compliance. The CTM leads Clinical Operations execution and serves as the primary point of accountability for trial delivery, working cross-functionally with internal teams and sponsors. What You'll Do

• Plan and manage all clinical operations activities across assigned trials to ensure delivery in line with scope, timelines, budget, and quality expectations.
• Oversee site lifecycle activities (start-up, activation, monitoring, and close-out) and remote/onsite monitoring.
• Lead and supervise project-specific operational activities of CRAs and SMAs; provide direction, training, and study performance oversight.
• Develop and implement site management and monitoring plans; maintain timely collection and maintenance of trial documentation in CTMS.
• Proactively identify risks and implement mitigation strategies; utilize metrics and dashboards to monitor study performance and quality; support data review and query management as needed.
• Collaborate with cross-functional teams (Project Management, Data Management, Finance) and build strong relationships with sponsors and external partners; provide status updates and key insights.
• Ensure adherence to ICH-GCP and regulatory requirements; support audit and inspection readiness.
• Participate in bid defense activities and contribute to process improvements and operational best practices. What We're Looking For
• Bachelor’s degree in life sciences or related field (or equivalent) with at least 1+ year of experience in a CTM or equivalent role (CRO or pharmaceutical environment).
• Experience managing Phase III and/or IV clinical trials across multiple therapeutic areas.
• Knowledge of risk-based monitoring (RBM) principles preferred.
• Experience managing North American studies.
• Ability to manage multiple studies and priorities in a fast-paced environment.
• Strong leadership, organizational, and problem-solving skills.
• Effective communication and stakeholder management skills.
• Willingness to travel (~15%). Nice to Have
• RBM principles knowledge (preferred). Compensation & Benefits
• Competitive salary within country guidelines.
• Various annual leave entitlements.
• Health insurance offerings to suit you and your family’s needs.
• Competitive retirement planning offerings.
• Global Employee Assistance Programme (LifeWorks) with 24-hour access to support.
• Life assurance.
• Flexible country-specific optional benefits including childcare vouchers, bike purchase schemes, and discounted gym memberships.
• Additional benefits available on ICON careers site.