实验室研究助理/研究员

BioNTech in Zhuhai, Guangdong, is seeking a laboratory research assistant/researcher. The role focuses on cellular biology and antibody-related research in tumor biology, with opportunities to participate in in vitro and in vivo studies, data analysis, and documentation. The position involves collaboration with cross-functional teams to support project goals and ensure high-quality research output.

• Maintain culture, freezing, and revival of tumor cells and primary cells.

• Assist in isolating, inducing, expanding, and phenotyping PBMC-derived cells (T cells, B cells, NK cells, dendritic cells, macrophages, etc.).

• Support cell functional assays, including generating stable cell lines, cell binding assays, reporter gene assays, in vitro cytotoxicity assays, and cytokine release assays.

• Contribute to development, optimization, and validation of antibody in vitro activity assays.

• Perform antibody activity evaluation experiments and analyze data.

• Participate in establishing and assessing a bispecific antibody (BsAb) activity detection platform.

• Assist in antibody molecule screening and optimization.

• Help with in vivo pharmacology studies (PK/PD), pharmacokinetics, and safety evaluations.

• Support IND-related documentation preparation and technical inputs.

• Contribute to new project initiation assessments and technical feasibility analyses.

• Support the construction and optimization of cell activity detection platforms.

• Write and maintain SOPs, experimental records, and research reports.

• Perform other tasks assigned by supervisors.

• 3–5 years of relevant experience with a bachelor’s degree or higher in pharmacy, cell biology, molecular biology, immunology, biotechnology, or related fields.

• Experience in cell culture and functional assays; proficient in ELISA, flow cytometry, immunofluorescence, and reporter gene assays.

• Familiarity with data analysis software such as FlowJo and GraphPad Prism.

• Strong analytical and problem-solving abilities, with a willingness to learn new techniques.

• Excellent communication, teamwork, and writing skills.

• Experience in developing in vitro efficacy evaluation platforms is a plus.