Biomarker Group Leader (Principal Scientist)

Job title: Biomarker Group Leader (Principal Scientist)

About the Role

At Roche/CICoR, you will lead the biomarker team to accelerate translational science across Oncology, Immunology, Neurology, Cardiovascular & Metabolism, and Ophthalmology in China. You will define China biomarker strategy for early and late-phase programs, serve as the biomarker SME on clinical development teams, and collaborate with global teams and CROs to deliver rigorous biomarker support that informs decision-making.

What You'll Do

• Lead and mentor a multidisciplinary biomarker team while also acting as a hands-on contributor
• Define and drive the China biomarker strategy for early and late-phase clinical development programs, including feasibility assessments and execution plans
• Serve as biomarker subject matter expert on clinical development project teams, advising on disease biology and biomarker science
• Support the generation and review of critical clinical development documents to ensure alignment with biomarker strategies
• Partner with global biomarker and project teams to execute biomarker studies, including data analysis, interpretation, and reporting
• Integrate preclinical, clinical, and real-world data to guide indication selection and develop patient enrichment strategies
• Design and lead forward and reverse translational research studies with internal and external partners
• Stay abreast of novel biomarker modalities and technologies to prioritize and harmonize biomarker platforms
• Lead biomarker assay outsourcing, including overseeing development, transfer, validation, and CRO execution for non-clinical and clinical studies
• Ensure data integrity through critical review and validation of CRO-generated results
• Identify, select, and manage external vendors and collaborators to ensure timely delivery of high-quality data

What We're Looking For

• PhD or MD in a relevant scientific field (e.g., Molecular Biology, Cell Biology, Oncology, Immunology)
• Minimum of 5 years of pharmaceutical industry experience in Translational Medicine, Clinical Development, or Biology research, with a strong preference for biomarker experience
• Proven experience in end-to-end clinical drug development, including drafting protocols and ICFs, and cross-functional interfaces
• Deep familiarity with the regulatory landscape and competitive environment in China
• Extensive knowledge of state-of-the-art biomarker technologies, including immunoassays, NGS, IHC, FACS, PCR, and imaging modalities
• Demonstrated expertise in generating and interpreting data from diverse sample types to establish proof of biology, support dose selection, and develop enrichment strategies
• Ability to thrive in a dynamic, inclusive environment with accountability for personal contributions and development
• Strong leadership, collaboration, and communication skills; ability to influence stakeholders; proficient in English and Chinese