Biochemist I

POSITION SUMMARY:

• This job is responsible for manufacturing products using instruments and biochemical processes. The incumbent will utilize techniques such as gel filtration, centrifugation, spectrophotometry, reconstitution, and various assays.

DUTIES AND RESPONSIBILITIES

• Buffer exchanges protein solutions via spin column gel filtration to prepare conjugation/coating solutions or remove free-tag.

• Conjugates antibodies with Biotin or SULFO-TAG™ NHS-Ester in order to produce detection/capture antibodies for use in catalog and custom kits.

• Reconstitutes antibody materials for use in conjugation and buffer exchange procedures.

• Quantifies protein concentrations utilizing techniques such as spectrophotometry or BCA Assay.

• Runs assays to quantify biotin/protein ratios or glycerol content in solution.

• Participates in developing solutions to improve routine manufacturing initiatives that provide for better quality and quantity of products.

• Documentation

o Completes appropriate documentation to support process and production procedures including data entry and production batch records.

o Performs daily maintenance and documentation of all production equipment.

• Participates in general laboratory maintenance including maintaining laboratory cleanliness, supplies and equipment.

• Prepares, maintains and reports raw material or reagent inventories.

• Participates in year-end physical inventory.

• Specific duties may vary depending upon departmental requirements.

EXPERIENCE AND QUALIFICATIONS

• Bachelor’s degree in Biology, Chemistry, Biotechnology, Engineering or related field; or an Associate’s degree with equivalent applicable work experience.

• Internship experience in relative field is highly desirable

• Prior manufacturing experience is a plus.

KNOWLEDGE, SKILLS AND ABILITIES

• A demonstrated aptitude for learning and adhering to standard laboratory techniques and safety precautions

• Knowledge of JDE is preferred

• Knowledge of cGMP and/or ISO certification is highly preferred

• Ability to learn additional software applications/tools, as required

• Ability to follow laboratory safety instructions; ability to use protective equipment.

• Knowledge of scientific fundamentals and possess a strong analytical background

• Mechanical aptitude including equipment troubleshooting

• Excellent oral, written communication and interpersonal skills

• Ability to effectively communicate issues/problems and results that impact timelines, accuracy and reliability of laboratory data

• Proficiency in MS Office Suite

• Ability to multi-t