Associate Director, Stem Cell Research

Associate Director, Stem Cell Research

General Summary:

Vertex is looking for a highly motivated candidate with experience in human pluripotent stem cell culture and directed differentiation protocols to lead our cell Foundry, a collaborative team focused on stem cell-derived islet (SC-islet) production, and associated workflows, enabling Vertex’s Cell & Gene Therapy pipeline with a current focus on Type-1 diabetes (T1D) program. This leader will manage and oversee a group of talented scientists and collaborations to advance T1D program goals and accelerate discovery. The ideal candidate is a strong and collaborative team leader who is detail-oriented, eager to learn, and innovate cell therapy processes. This role requires excellent communication and organizational skills, as well as adaptability and the ability to manage multiple priorities in a fast-paced research environment.

Key Duties and Responsibilities:

• Manage cell Foundry team in support of key deliverables across T1D programs in stem cell, islet cell, and/or immunology needs
• Lead efforts to innovate, streamline, and automate processes for stem cell expansion and directed differentiation to various cell types focusing on stem cell-derived islets (SC-islets)
• Manage project prioritization and communication with project leadership to achieve key deliverables supporting Vertex’s Cell & Gene Therapy research including key IND-enabling activities
• Partner with stakeholder teams to plan, coordinate, and execute experiments across different cell types and cell lines
• Leverage analytical tools to evaluate the molecular characteristics of stem cells, differentiation intermediates, and stem cell-derived islets (SC-islets)
• Present findings to the group and collaborators with summarized data in reports and presentations
• Motivate team, ensure alignment with goals, and resolve conflicts
• Construct draft-budgets and manage execution of approved budgets
• Ensure group adherence to electronic laboratory records, database entries, and data integrity standards
• Performs other duties as assigned
• Drafting and oversight of high-quality departmental documents for regulatory submissions, manuscripts, abstracts and publications.
• Act as a subject matter expert and assist others outside of own project with troubleshooting and data interpretation.
• Build and maintain strong collaborative partnerships with other R&D disciplines to advance Vertex programs through discovery and development.
• Work with corporate legal to identify and file intellectual property on novel and inventive discoveries.
• Helps craft department goals and strategies to ensure effective achievement of broader company scientific objectives.

Knowledge and Skills:

• Possesses a distinguished record of cross-functional collaboration to achieve team goals through prioritization and efficiency
• Demonstrated excellence leading high-performing teams with core management experience a plus
• Exhibits a basic understanding of molecular & cell biology beyond his/her own specialty area
• Demonstrates strong aptitude helping to lead a group or team endeavor, and building team unity
• Demonstrates advanced judgement balancing technical feasibility, opportunity and impact
• Communicates clearly and precisely (reading/writing and verbal) with all levels of the company
• Distinction achieved by mentoring subordinates, addressing organizational problems, maintaining procedural and ethical standards, and cultivating healthy team morale
• Demonstrates initiative and ability to capitalize on scientific creativity and insights

Education and Experience:

• Ph.D. (or equivalent degree) in molecular biology, cell biology, biochemistry, or related disciplines and 4-7 years of relevant post-doctoral employment experience, or
• Masters Degree (or equivalent degree) in molecular biology, cell biology, biochemistry, or related disciplines and 7+ years of relevant employment experience, or
• Bachelors Degree (or equivalent degree) in molecular biology, cell biology, biochemistry, or related disciplines and 10+ years of relevant employment experience

At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.

Pay Range: $169,500 - $254,300

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation: On-Site Designated

Flex Eligibility Status:

In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

LI-Onsite

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

About Vertex

Help Us Achieve Our Mission

Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has approved medicines that treat the underlying causes of multiple chronic, life-shortening genetic diseases — cystic fibrosis, sickle cell disease and transfusion-dependent beta thalassemia — and continues to advance clinical and research programs in these diseases. Vertex also has a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases where it has deep insight into causal human biology, including APOL1-mediated kidney disease, acute and neuropathic pain, type 1 diabetes, myotonic dystrophy type 1 and alpha-1 antitrypsin deficiency .

Founded in 1989 in Cambridge, Mass., Vertex's global headquarters is now located in Boston's Innovation District and its international headquarters is in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia, Latin America and the Middle East. Vertex is consistently recognized as one of the industry's top places to work, including 14 consecutive years on Science magazine's Top Employers list and one of Fortune’s 100 Best Companies to Work For. For company updates and to learn more about Vertex's history of innovation, visit www.vrtx.com or follow us on Facebook, Twitter/X , LinkedIn, YouTube and Instagram.

The diversity and authenticity of our people is part of what makes Vertex unique, and we recognize that each employee brings diverse perspectives and strengths. By embracing those strengths and celebrating differences, we are fostering an inclusive culture where each of us can bring our authentic selves to work, inspire innovation together, and change people’s lives.

Our vision is clear: to be the place where an authentic, diverse mix o