About this role
About the Role Latigo Biotherapeutics, Inc. is a private, early-stage biotechnology company focused on discovering and developing the next generation of non-opioid medicines for pain and pain-related syndromes. Our mission is the development of novel therapies that transform the lives of patients. The company, headquartered in Thousand Oaks, CA with a satellite office in San Francisco, CA, has a highly successful management team as well as an experienced Board of Directors. The Associate Director, Clinical Pharmacology will be a key member of the clinical pharmacology group, contributing to the development of Latigo's pain programs in a hybrid role based in the San Francisco Bay Area or Thousand Oaks.
What You'll Do
- Design and lead the clinical pharmacology program to support candidate selection and development plans.
- Quantify PK/PD relationships and inform dosing strategies through modeling and data analysis.
- Build and maintain PK/PD models; apply modeling and simulation to inform go/no-go decisions and clinical development strategies.
- Provide pharmacology input to regulatory submissions, development plans, and cross-functional programs (Clinical Development, Translational Sciences, Regulatory Affairs).
- Collaborate with multidisciplinary teams to integrate translational data and support risk-based decision making.
- Mentor and lead junior scientists; manage study timelines and deliverables.
What We're Looking For
- PhD or MD in pharmacology, pharmacokinetics, pharmaceutical sciences, or a related field.
- 7-12+ years of industry experience in clinical pharmacology, preferably in biotech or pharmaceutical settings.
- Proven track record leading clinical pharmacology programs and collaborating across cross-functional teams.
- Strong communication and leadership skills; ability to influence decisions and convey complex data clearly.
- Expertise in PK/PD modeling, exposure–response analyses, and clinical trial design; experience with regulatory discussions is a plus.
Nice to Have
- Experience in pain therapeutics or early-stage biotech development.
- Familiarity with modeling tools such as NONMEM, Monolix, Phoenix, or similar platforms.
- Experience working in a fast-paced startup/biotech environment and contributing to regulatory interactions.