Senior Principal Scientist/Associate Director Clinical PBPK (Dual Level Posting)

Senior Principal Scientist/Associate Director Clinical PBPK (Dual Level Posting)

The Modeling & Simulation group within PK Sciences is looking for a Principal Scientist to Associate Director level modeler, to develop and apply translational physiologically based pharmacokinetic (PBPK) modeling along with data analysis techniques to facilitate drug discovery, development, and translational research across disease areas. Importantly, the candidate has experience with regulatory submissions and in successful regulatory interactions. The candidate’s core responsibilities will include PBPK modeling to integrate in vitro and in vivo data for drug-drug interaction (DDI) assessments, impact of biopharmaceutics properties on absorption, and pharmacokinetic (PK) predictions in humans as well as in specific populations (e.g. disease, organ impairment, pediatrics).